A knowledge resource for innate immunity interactions & pathways

Genes and proteins

Search for genes and proteins of interest.

Interactions

Search and visualize experimentally-verified molecular interactions by gene/protein name, interaction type, cell type, etc.

Pathway Analysis

InnateDB Pathway Analysis enables users to determine which biological pathways are statistically over-represented in a given gene/protein list.

Analysis

Gene Ontology Analysis

Determine which biological pathways are statistically over-represented in a given gene/protein list.

Analysis

Network Analysis

Build, visualize and analyze the molecular interaction networks that a gene list of interest and their encoded products are components of.

Analysis

Innate Immunity Genes

Literature curation of innate immune genes.

Statistics

Statistics for manually-curated innate immunity relevant molecular interactions. New manually curated interactions are submitted weekly.

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About InnateDB

InnateDB is a publicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures an improved coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralised resource. To date, 18,780 interactions have been manually curated by the InnateDB curation team. The database can be mined as a knowledgebase or used with our integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response.